Senior Principal Engineer, Tech Ops

The Opportunity

The Senior Principal Engineer serves as a global technical leader and subject matter expert (SME) within Technical Operations. This role provides guidance across the product and process lifecycle, influencing strategy, driving global improvements, and ensuring robust, compliant, and efficient operations across the network.

The Senior Principal Engineer leads complex, crosssite or global initiatives, mentors technical staff, and represents the function in highimpact forums internally.

Serve as an enterpriselevel SME for critical process technologies and unit operations, providing authoritative technical guidance across sites.

Represent MS&T in global governance bodies, design reviews, and strategic initiatives.

Own stewardship for defined process families, technology platforms, or system categories across the network.

Provide expert input for technology strategy, modernization roadmaps, and longterm capability building.

Oversee lifecycle performance of assigned processes, equipment, and products across multiple sites, ensuring consistency, robustness, and compliance.

Lead or provide expert direction on technology transfer, scaleup/scaledown, modernization, and lifecycle management projects.

Drive harmonized standards, best practices, and templates across the enterprise.

Serve as escalation point for complex, multisite technical challenges, facilitating structured problem solving and datadriven decisions.

Lead resolution of highrisk deviations and CAPAs, ensuring enterprise learning and preventive improvements.

Analyze production and analytical data to assess global performance, identify trends, and prioritize improvements.

Guide the use and maturity of riskbased tools (FMEA, PRA) across sites.

Lead or contribute to global S&I and/or OPEX/CAPEX projects involving multiple sites or functions.

Oversee technical execution ensuring alignment with regulatory expectations and strategic goals.

Provide technical duediligence, conceptual design input, and architecture for largescale changes.

Define and lead networklevel continuous improvement initiatives to drive yield, reliability, efficiency, cost, and sustainability improvements.

Advance global harmonization and standardization efforts for processes, systems, equipment, and documentation.

Develop riskbased validation strategies for global programs, enabling efficient, compliant, and sciencebased execution.

Contribute to inspection readiness activities (internal and regulatory), including preapproval inspections.

Review highimpact technical justifications and regulatory submissions.

Lead multisite, multifunctional teams to deliver enterprise outcomes.

Serve as a trusted strategic partner to Manufacturing, Quality, Engineering, R&D, and Global Functions.

Build consensus across diverse stakeholders and influence without authority, ensuring alignment with enterprise goals.

Act as a role model for safety, adhering to all site guidelines, proactively mitigating risks, and supporting a culture of safety excellence.

Mentor engineers, scientists, and site personnel to elevate technical skills, decisionmaking, and problemsolving capability.

Support development of training materials, technical standards, and communities of practice.

Act as a thought leader, representing the company in industry forums as appropriate.

Bachelor’s degree in Engineering, Life Sciences, or related discipline required.

Advanced degree strongly preferred (MS or PhD).

7+ years experience in pharmaceutical/biotech operations, MS&T, Process Engineering, Process Technology, or related disciplines.

Demonstrated expertise leading global or crosssite programs, major capital projects, or enterprise transformations.

Significant experience supporting regulated environments (GxP, OSHA, EPA), including inspections.

Strong track record of technical leadership, complex problem solving, and strategic influence.

Leadership

Think Beyond: Incorporates external market/technology trends and anticipates strategic implications.

Inspire the Future: Shapes and communicates global technical vision.

Build Bridges: Leads cross-business collaboration; influences without authority.

Cultivate Talent: Mentors and strengthens technical capabilities across sites.

Unleash Outcomes: Drives enterprise-level results with accountability for global impact.

Technical

Expertise in global lifecycle management and multi-site operations.

Strong capability in data-driven strategy and network-level performance oversight.

Deep understanding of regulatory expectations and inspection readiness at a global scale.

Behavioral

Executive communication and stakeholder influencing.

Strategic decision making under complexity.

Ability to drive harmonization and change across cultures and geographies.

Serve as global SME for defined technologies, equipment families, or process platforms.

Lead complex or high-impact cross-site investigations and CAPA strategies.

Guide multi-site technology transfer, scale-up/down, modernization, and harmonization initiatives.

Define and lead global continuous improvement programs.

Contribute to global validation approaches and support regulatory submissions.

Represent MS&T in global governance forums and strategic technical bodies.

Mentor engineers and build enterprise technical capability.

Collaborate with senior leaders to align global priorities and technology roadmaps.

CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients’ needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.

CSL Behring operates one of the world’s largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries.

To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor  visit and CSL Plasma at .

Our Benefits

For more information on CSL benefits visit How CSL Supports Your Well-being | CSL .

You Belong at CSL

At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future.

 To learn more about inclusion and belonging visit

Equal Opportunity Employer

CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit .