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Senior Backend EngineerOrchestra Bio, IncUnited States

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Senior Backend Engineer

Orchestra Bio, Inc
  • US
    United States
  • US
    United States

Über

The Role
We're seeking a Senior Backend Engineer to join our growing team in San Francisco. You'll work with our team to create complex but intuitive products to manage R&D. Challenges You'll Tackle
Complex Decision Making : Build interactive tools that help organizations model different paths to market for their discoveries, assessing complex trade offs between time, money, and technical risk. Our users need to understand how decisions today affect their programs years into the future. Organizational Alignment : Create intuitive interfaces that help diverse teams (scientists, program managers, executives) understand how their work connects to broader company goals. This includes designing clear ways to visualize complex dependencies and communicate progress across teams. Scientific Operations : Design interfaces that scientists and researchers use daily to manage their studies, track progress, and coordinate with their teams. This requires crafting experiences that empower rather than get in the way of work. AI Powered R&D Management : Leverage LLMs to help teams generate and evaluate scenarios, infer scientific progress and risks from unstructured data, and surface critical insights from across their R&D portfolio. What Sets You Apart
Complexity : You understand how to build backends for complex, interconnected systems where changes in one area cascade across multiple dimensions. You're excited about creating infrastructure that handles the unique challenges of long term, high stakes R&D programs. Agency : You're drawn to environments where you can shape both the technical architecture and product direction. You enjoy the responsibility of building foundational systems that will scale, balancing the speed needed at an early stage company with the craftsmanship required for complex, mission critical software. Curiosity : You're genuinely curious about how breakthrough products are developed and excited about building software that helps scientific organizations operate more effectively. You want your technical work to contribute to bringing medicines and other innovations to market. Qualifications
Required
6-8 years of backend development experience with production systems at scale
Deep expertise in Typescript, NestJS, PostgreSQL
Track record of building complex, scalable, reliable cloud-based software
Experience with cloud platform (AWS/Azure/GCP) and containerization
Strong experience in data modeling and API design
Collaborative mindset with proven track record of working effectively in small, fast-moving engineering teams
Preferred
AI/ML integration with OpenAI, Anthropic, or similar LLM providers
Prompt engineering and RAG implementation experience
Full-stack capabilities - can contribute to frontend when needed (React/TypeScript)
Track record of mentoring other engineers
  • United States

Sprachkenntnisse

  • English
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