Senior Mechanical Design Engineer, Automation

Job Description:

Are you ready to revolutionize Cell & Gene Therapy? Join us in shaping the future of therapeutics We are seeking a Senior Mechanical & Automation Engineer in our journey of developing cutting-edge manufacturing solutions for Casgevy—a first-of-its-kind therapy transforming the treatment of Sick Cell Disease and Beta Thalassemia. In this role, you will be at the forefront of automating complex processes in one of the most dynamic and rapidly evolving fields in biotechnology. By leveraging your expertise in mechanical engineering and automation, you will play a pivotal role in streamlining manufacturing, enhancing manufacturing reliability, and scaling life-saving therapies to reach patients faster. You will work with a passionate team of scientists, engineers, and innovators, all united by a shared mission: to push the boundaries of what's possible in Cell & Gene Therapy. This role reports to the Associate Director of Automation, Equipment, and Processes.

Key Responsibilities:

• Development of industrial machinery and automation from concept through commercial deployment.
• Manage the evaluation and selection of new equipment/technologies or modifications to existing systems required for scale up.
• Mechanical Design and integration, including, but not limited to robotics, single-use sets, single-use set cartridges, conveyors, AGV/AMRs, cam-followers, peristaltic pumps, pinch valves, MFCs, Solenoid valves, and process analytical technologies, and more.
• Mechanical Design Analysis, including, but not limited to kinematic design & analysis, dynamic analysis, stress analysis, tolerance stack analysis, mechanism design, cycle time calculation, utilization calculations, and cam-follower design.
• Aseptic and GMP design. Design for compatibility with cleaning and sterilization. Single Use Set Design experience.
• Interface and collaborate with controls resources for joint electro-mechanical designs.
• Manage vendors and perform design reviews, FATs, and SATs. Support validation activities.
• Create a scale up plan from concept through commercial equipment deployment.
• Provide support to non-engineering Staff, including those from R&D and Manufacturing, to ensure successful technology