Post-Doctoral Researcher

IrishJobs

Dublin, Dublin, Ireland

Dublin, Dublin, Ireland

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Job Title: Post-Doctoral Researcher Department: Surgery Reporting to: Prof Leonie Young, Dr Damir Vareslija Location: York House, RCSI, St Stephens Green, Dublin 2 Contract/Duration: Specified purpose contract, up to 2 years Remuneration: Up to Point 5 on the IUA Post Doctorate Researcher (PD1) pay scale, depending on experience Closing Date: 29th May 2026 RCSI is a community of academic, research, clinical and professional staff working collaboratively to lead the world to better health. Here, you will thrive in an innovative and inclusive atmosphere and your personal development and wellbeing will be supported. We invite you to join us to help deliver on our exciting mission "To educate, nurture and discover for the benefit of human health". We seek candidates whose experience to date has prepared them to contribute to our commitment to the "Race Equality Action Plan 2025-2029" at RCSI. Our students come from all walks of life and so do we. We hire great people from a wide variety of backgrounds. This makes our university stronger and ensures we hire the best talent. Innovating for a Healthier Future 2023-2027 is RCSI's new five-year strategic plan. Through it, RCSI will enhance human health by meeting the health workforce needs of society, creating the insights and inventions that drive health improvements, and working in partnership with patients and the public in support of better health and well-being for all. The strategy unites the RCSI community in supporting the UN Sustainable Development Goals - with a particular focus on Goal 3, which targets good health and well-being. For each of the last six years, RCSI has been positioned in the Top 300 of universities worldwide in the Times Higher World University Rankings. We are proud that RCSI ranks first in the world for "Good Health and Well-being" in the Times Higher Education #SDG #SDG Impact Rankings 2025. This reflects our commitment to supporting people of all ages to live healthy lives and our work to promote the concepts of well-being and positive health. In 2024, RCSI was delighted to be named one of the Sunday Times Best Places to Work in Ireland. At RCSI, our core values of Respect, Collaboration, Scholarship, and Innovation are at the heart of everything we do. We are committed to creating an inclusive and supportive environment where every colleague is valued and empowered to thrive. Our dedication to these values ensures that we foster a culture of mutual respect, open collaboration, continuous learning, and innovative thinking. Join us at RCSI, where your contributions will be recognised, and you will be part of a dynamic team making a real impact on global health. About Our Research RCSI recognises that excellence in research is critical to the quality of its educational activities, its credibility, and, overall, to its mission to enhance human health. RCSI's research strategy aims to build upon its strength in translational biomedical and clinical research to deliver transformational, high impact changes in health care. Targeting both Irish national and EU funding, along with increased collaboration with industry, is a major part of the RCSI research strategy. Forging increased collaboration between RCSI PIs and industry is of critical importance to achieving success in this area. RCSI is also committed to provide its researchers with the supports and developmental opportunities to enable them to continuously grow and support their overall career development. Summary of Post We are seeking a post-doctoral researcher for the Research Ireland Strategic Partnership programme PRISM, which focuses on breast cancer brain metastasis (BCBM). BCBM are a frequent and aggressive form of metastatic spread with limited treatment options. The successful candidate will join Prof Leonie Young and Dr Damir Vareslija and their team to identify the molecular mechanisms controlling the evolution of metastasis in breast cancer and define key regulators of metastatic spread. By mining multi-omic (genomic, transcriptomic and proteomic) data, new druggable targets gained in BCBM will be identified. Key genes, core to the tumour adaptive process, will be identified, providing a platform for discovery of new metastatic drug targets. Drug target validation will be undertaken using spatial genomics and advanced tissue imaging. This novel approach will provide innovative therapeutic targets less susceptible to resistance The research project will be conducted in a highly collaborative environment. The successful candidate will be expected to design and carry out experimental plans, lead study execution, analyse experimental data, prepare manuscripts and mentor PhD students. The candidate will also be expected to support other ongoing research projects in the lab. Specifically, the duties of the post are: To lead a study to determine the metastatic oncogenic signals in BCBM and identify novel therapeutic targets To independently plan, execute, analyse, and manage multiple experiments simultaneously To maintain accurate, detailed records of experimental data and protocols To create visually impactful representations of data for publications and presentations To work in a team environment and, as needed, train new personnel and mentor postgraduate students as required Contribute to the preparation of high-impact peer review scientific publications and to disseminate research findings at national and international meetings To attend courses and meetings as appropriate to maintain up to date knowledge. To perform any other duties as may be appropriate to the grade or as determined to be required for the purposes of PRISM research grant. Qualifications - (Essential): The candidate should have a higher degree (PhD or equivalent) in the area of cancer research/molecular biology or relevant area. Knowledge & Experience - (Desirable): Expertise in advanced molecular and translational cancer research techniques, including functional genomics and epigenomics, genome engineering, and the use of patient-derived and preclinical models to investigate mechanisms of metastasis and treatment resistance. Evidence of a strong research track record, demonstrated through first-author and co-author peer-reviewed publications in relevant fields, is highly desirable. Experience in translation of novel therapeutics. Bioinformatic and statistical analysis skills. We are all too aware that imposter syndrome and the confidence gap can sometimes stop fantastic candidates putting themselves forward, so please do submit an application - we'd love to hear from you. Application Process Please apply online through the RCSI careers portal on the closing date with your CV and cover letter. Informal Enquiries can be directed to Dr Damir Vareslija at . Please note we do not accept CVs directly. Click here to read our Recruitment and Selection Policy for Researcher. Garda vetting and occupational health review may be required for this role, depending on the nature of the duties and responsibilities. Further information will be provided during the recruitment process. Eligibility to Work in Ireland Visa sponsorship is available for candidates who fully meet the essential criteria of the role. Candidates who require a work permit or hosting agreement are welcome to apply. Proof of eligibility documentation will be required at a later stage in the recruitment process. Please note that sponsorship is subject to approval by the relevant Irish authorities and role-specific eligibility. Employee Benefits At RCSI, we help care for our people so they can focus on our mission to Educate, nurture and discover for the benefit of human health. RCSI truly goes above and beyond to support its employees, ensuring they have everything they need to thrive both personally and professionally. Here's a glimpse of the fantastic benefits available: Health and Wellbeing: Our Inspire Programme promotes the importance of taking care of both our general health and mental health. Inspire manages the Employee Assistance Programme (EAP) offered through SpectrumLife. Past events held by Inspire have included, workshops on mindfulness practices, yoga, nutritional advice, financial advice on mortgages, pensions & health insurance from leading experts, fitness challenges, baking competitions, weight loss programmes, annual flu vaccination campaign and many more. You can also enjoy access to an onsite gym for just €10 per month. Work -Life Balance: Maintaining a healthy work-life balance is crucial for fostering employee well-being, productivity, and overall satisfaction. At RCSI, we offer flexible working arrangements, study leave, and career breaks. In addition to 20 days of annual leave, employees receive an extra 6.5 days of university privilege days, which occur annually around the Christmas and Easter breaks. Family Benefits: RCSI offers enhanced family leave to our working parents with fully paid Maternity, Adoptive, Paternity and Surrogacy Leave. We also offer the first two weeks of Parents leave fully paid for, as well as the option to take Parental Leave until your child is 18 years old. We provide access to Platform 55, a new Parents Platform to support staff before, during, and after becoming a parent. We also offer flexible working, discounted Giraffe crche services of up to 20% and a Parents and Carers' Network. Financial Security: Benefit from automatic enrolment in a pension scheme with Willis Towers Watson with the employer contributions increasing with your length of service, Death in Service of up to 4 times your salary, long-term illness and disability income replacement, and free advice on health, motor, and home insurance. Discounted Services: Avail of discounted GP services, Taxsaver commuter tickets, the BiketoWork scheme, free eye tests at the National Optometry Centre, and discounted parking at St. Stephen's Green/RCSI car park. Recognition: At RCSI, we value and recognise the contributions of our staff through various awards and events, such as Long Service recognition, the Vice Chancellor Staff Awards, and through Research Day. Professional Growth: RCSI's Staff Learning and Development is committed to providing colleagues with opportunities and support to help them reach their full potential and thrive at work. Offerings include a comprehensive programme of staff training, management and leadership development, mentoring, coaching and funding support for further study. Staff Networks: Additionally, we support a range of staff networks, including the Women's Network, Postdoctoral Staff Network, Parents & Carers' Network, Project Manager's Network, LGBTI+ Network, Age Friendly Network etc. These networks help RCSI to foster a sense of community and inclusivity. Sports and Social Club: Engage in a variety of activities such as Yoga, Pilates and a variety of different Fitness classes. Enjoy social evenings, Book Clubs, Summer BBQs and one-off events like the Taste of Dublin, Bloom, Dublin Horse Show and Dublin Zoo. We also have a variety of discount tickets for shows and events through the year. Note: This job description may be subject to change to reflect the evolving requirements of the Department and RCSI. Similar vacancies that arise in the next 6 months may be filled from the pool of applicants that apply for this position. RCSI is proud to be an equal opportunity employer and welcome applications from all suitably qualified persons regardless of their gender, civil status, family status, sexual orientation, religion, age, disability or race. RCSI is committed to embedding equality, diversity and inclusion (EDI) across everything we do. This ensures we can all work and learn in an environment defined by dignity and respect. Eligibility to work in Ireland is a requirement of this role, Proof of eligibility documentation will be required at a later date. Under limited and specific circumstances (research/ specialist roles) RCSI may be in a position to seek a hosting agreement and/or work permits. Employees are required to undertake 6 months service in their current role before applying for other internal opportunities, unless agreed in advance by the SMT representative

TLNT1_IJ

Dublin, Dublin, Ireland

Compétences linguistiques

English

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