Applications Scientist

What we do:

At SilcsBio we are passionate about accelerating the pace of drug discovery. We are scientists, programmers, and innovators developing and utilizing physics-based computer-aided drug design (CADD) tools in conjunction with machine learning technologies to help researchers in small molecule and biologics development. Our patented Site Identification by Ligand Competitive Saturation (SILCS) technology enables all aspects of small molecule drug design, protein-protein interaction modulation, antibody-drug conjugate development, and protein formulation.

We are seeking an
Applications Scientist
with expertise in computational chemistry or cheminformatics
and strong software development skills
to support software development, deployment, and internal systems administration.

What you will do:

• Collaborate with a dynamic, multidisciplinary team supporting both internal R&D and external customer projects.
• Design and implement novel applications and features into the SilcsBio GUI and backend software.
• Build and maintain software packaging and deployment pipelines for Linux, Windows, and macOS.
• Manage and maintain internal HPC cluster (Linux-based), including performance monitoring and troubleshooting.
• Provide technical support and guidance to customers on installation, usage and application of SilcsBio software.
• Contribute to the development and optimization of computational workflows for drug discovery and development.

What you need to be successful:

• A Ph.D. in
  Computational Chemistry
  ,
  Cheminformatics
  , or a related field.
• Strong programming skills in
  Python
  and
  C++
  for backend development and experience developing cross-platform GUIs using
  JavaScript
  frameworks (e.g., Electron, Vue, React).
• Experience with
  Linux systems administration, network management
  and HPC environments.
• Familiarity with software packaging tools (Conda, Docker, installers) and version control (Git).
• Excellent problem-solving skills and ability to work independently in a fast-paced environment.

Who will you work with:

At SilcsBio, we prioritize
career development
and professional growth. You will work alongside
senior scientists, business leaders, and customers worldwide
, gaining hands-on experience in both scientific research and industry applications.

Benefits:

• Flexible holiday policy – you choose your own holidays
• Paid vacation and sick leave
• Medical, Life and Dental Insurance
• 401K with matching

How to Join Us:

Please send your resume and cover letter to Ken Malone