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Research Associate II - ManufacturingAmprion GmbH • San Diego, California, United States
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Research Associate II - Manufacturing

Amprion GmbH
  • US
    San Diego, California, United States
  • US
    San Diego, California, United States
Postuler Maintenant

À propos

Company Description - Amprion
Amprion is the global leader in advancing the diagnosis of neurodegenerative disorders through the development and application of Seed Amplification Assays (SAA). Our technology empowers precision medicine by enabling early, accurate detection of misfolded proteins associated with diseases like Alzheimer's, Parkinson's, and Lewy body dementia.
Historically, diagnosis and treatment of neurodegenerative diseases have been symptom-driven, often resulting in misdiagnosis and delayed care. Many patients endure a "diagnostic odyssey," seeking answers that are often not confirmed until autopsy. With limited tools available, physicians have historically had to rely on their best judgment rather than definitive biological evidence.
Amprion's SAAmplify™ platform changes that paradigm. By enabling highly sensitive, early detection of disease-causing proteins, we provide critical biological insights that support earlier intervention, enhance clinical trial recruitment, and accelerate the discovery of disease-modifying therapies. Our mission is to help end the global burden of Alzheimer's, Parkinson's, and other neurodegenerative disorders through groundbreaking diagnostic solutions
Position Description
This role reports to the Manager, Component Production and Supply Chain. Responsible for executing experiments that facilitate the development, optimization or modification and validation of assays used in the clinical laboratory. May contribute to experimental design and data analysis.
Responsibilities
Ensure adherence to laboratory safety and quality control procedures.Familiarity with fermentation and purification process design limits for implementation in an ISO 13485 manufacturing environment.Proficient in operating and troubleshooting E. coli fermentation and AKTA chromatography systems. (5-20L scale)Experience conducting fermentation and purification development and optimization studiesMaintain detailed and accurate laboratory notebooks, as applicable.Participate in and/or facilitate reagent and supply inventory management.Work closely with cross-functional teams and participate in/contribute to meetings as required.May assist with equipment preventative maintenance and troubleshooting, preparation and storage of reagentsPerforms other duties as required
Qualifications
Degree: Bachelor's Degree in Chemistry, Biochemistry, Neuroscience, Biology, or related discipline.Experience working in a protein manufacturing facility required. Excellent written, oral and collaboration skills.Experience with regulatory bodies (ISO13485) preferred.
Physical Requirements
This role works in the Manufacturing Laboratory and office space. While performing the duties of this job, the employee is regularly required to sit, talk, hear, operate equipment and a computer. The employee is occasionally required to stand, walk, and use hands and arms to lift and/or move up to 40 lbs. Specific vision abilities required by this job include close vision, and the ability to adjust focus.
In this work environment, the employee is occasionally exposed to moving mechanical parts, unpleasant odors, and loud noises. Interaction with laboratory equipment, samples, supplies and laboratory personnel may be required whereby appropriate precautions are to be taken per the company's Safety and Injury, Illness and Prevention Plans.
Compensation
Base salary range of $70k-$85k
Bonus potential
Private company stock options
100% paid EE medical, dental, vision coverage
  • San Diego, California, United States

Compétences linguistiques

  • English
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