Job Opportunities

At Alnylam, all late-stage development and commercial programs are managed by a Global Program Leadership Team. The Global Program Leadership Team for TTR, the TTR Franchise Leadership, includes the TTR Franchise Lead, the TTR Program Leader(s), the TTR Franchise Program Manager(s), and representative expertise areas (EAs). The TTR Franchise Program Manager(s) are responsible for helping lead a multi-disciplinary program team, comprised of functional representatives from Clinical Development, Regulatory Affairs, Legal, Technical Operations and Quality (TOQ), and Medical Affairs, Market Access, and Commercial (MAC) to ensure success of the TTR Franchise.

The Director, TTR Program Manager serves as a strategic thought partner to the TTR Franchise Lead and the TTR Program Leaders, and is responsible for proactively operationalizing and executing the program strategy. The TTR Program Manager will ensure that all subteams are aware of their overarching objectives, deliverables, and timelines. Additionally, the TTR Program Manager will be responsible for providing a combination of drug development and program management expertise to the TTR Franchise Leadership Team and other relevant subteams, to maximize the potential of the TTR Franchise by ensuring smooth day-to-day operations, enabling timely communications across the teams, and supporting strategic decision-making. The TTR Program Manager will also coordinate activities associated with global regulatory submissions and launches, as well as life-cycle management planning.

The TTR Program Manager will also be responsible for accurately updating program management reports, timelines and dashboards and drive the identification/implementation of Program Management best practices within Alnylam. In this capacity, the Program Manager will call upon direct prior experience to implement proven drug development, commercial, and portfolio best practices and adapt them to the Alnylam Network Operating Model.

Summary of Key Responsibilities

• Partner with TTR Franchise Lead and TTR Program Leaders to develop and execute program strategy and ensure alignment across all expertise areas.
• Hands on development of Franchise workplans/timelines and integrated development plans with milestones/goals, key events, risks/assumptions and scenarios.
• Drive coordination of cross-functional activities and promote effective communications (e.g., Team meetings, meeting minutes, program updates); integration of people involved within the program (e.g. clarity of responsibilities). For efficiency, this is done through coordination and co-leadership of critical, defined sub-teams.
• Facilitate strategic planning discussions through scenario planning, development of risk mitigation plans and alignment of key program decisions through appropriate governance forums
• In partnership with the TTR Franchise Lead and TTR Program Leaders, ensure clear, timely, and substantive updates on Program progress and issues to Executive Management.
• Manage Leadership Team meetings, including leading discussions to drive to decision-making, agenda creation, and meeting minutes.
• Serve as a key point person for Leadership Team members, particularly on issue identification, resolution and escalation.
• Owner for key global program documents, e.g. global filing and launch plan, integrated development plan, risk plan, and additional key status and timeline updates.
• Provide expertise on program management initiatives including alignment of processes, tools, and technologies that aid in portfolio management across the organization.

Qualifications

• Minimum of 10 years total experience in pharmaceutical or biotechnology industry including work on a clinical-stage and/or commercial program
• Bachelor's degree in sciences or related field required; Advanced degree (PhD or MBA) highly preferred
• Passion for helping patients and developing transformative treatments for patients in need; motivated by patient focus and personal commitment to high performance and results
• Demonstrated proficiency in program management tools (e.g., Smartsheet, Microsoft Project) and methodology. Willingness to improve project management tools and skillset through best practices
• Demonstrated ability to work well in a collaborative, highly-networked and dynamic team environment, set priorities, and drive results
• Strong analytical and problem-solving skills; ability to combine attention to detail within broader strategic context
• Excellent written and oral communication, including presentation and facilitation skills
• Thrive in a fast-paced environment with strong ability to handle multiple activities simultaneously across the program and expertise area

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we've been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2022, one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2023 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK - among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law. Alnylam is an E-Verify employer.