Bioinformatics Engineer II

Help us change lives

At Exact Sciences, we're helping to give patients and clinicians the clarity needed to make confident decisions when they matter most. A purpose-driven career, an inclusive culture, and robust benefits await you.

The Bioinformatics Engineer II will analyze data from assays and software applications, designing new algorithms and applications to support our platforms and products.

This role entails partnering with Product Development teams on study design planning, analysis, and result interpretation, as well as gathering requirements to develop modules for software products.

The position requires a basic understanding of data structures and files commonly used in bioinformatics, along with basic knowledge of statistical methods.

• Design and implement bioinformatics analyses to support novel assays, assay improvement, and hypothesis testing requested by Product Development and Computational Biology teams.
• Collect and document product and software requirements and findings from analyses executed by themselves and others.
• Design and implement software modules implementing the requirements collected from data analyses.
• Assist with integrating software modules into pipelines.
• Manage bench-generated data and bioinformatics outputs within high-performance computing or cloud computing environments.
• Design and implement software modules to automate data analyses.
• Prepare and provide information and data for scientific abstracts, conferences, project meetings, publications.
• Identify and address trends in study data.
• Collaborate effectively in cross-functional teams.
• Communicate clearly through strong written and verbal skills.
• Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
• Support and comply with the company's Quality Management System policies and procedures.
• Maintain regular and reliable attendance.
• Act with an inclusion mindset and model these behaviors for the organization.
• Work designated schedule.
• Perform typing for approximately 50% of a typical working day.
• Travel up to 10% between local Exact Sciences locations.
• Travel up to 5% away from work location, may include overnight/weekend travel.

• Bachelor's degree in Software Engineering, Computer Engineering, Computer Science, or field outlined in essential duties.
• 4+ years of experience, or equivalent combination of experience and education outlined in essential duties.
• Extensive experience in Linux-based HPC or cloud computing environments and associated tools.
• Ability to write custom code in at least one programming or scripting language.
• Experience with software ticketing, progress tracking, and timeline tracking systems: JIRA, Smartsheet.
• Knowledge and adherence to good coding and documentation practices.
• Knowledge of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics.
• Working knowledge of statistical and mathematical methods in biology/genetics/genomics, including experience with statistical software, such as JMP or R.
• Basic computer skills to include Internet navigation, Email usage, and word processing.
• Proficient in Microsoft Office to include Excel, Word, and PowerPoint.
• Ability to perform essential duties with or without accommodation.
• Authorization to work in the United States without sponsorship.

• Advanced degree (PhD or Masters).
• 6+ years of relevant experience.
• Experience in an FDA-regulated environment, ideally in medical device development.
• Experience in a biotech manufacturing environment, preferably in a GMP and/or ISO environment.
• Familiarity with Laboratory Information Management Systems (LIMS), Next-Generation Sequencing (NGS), and clinical and diagnostic test development.
• Experience with PDP (Product Development Process) and/or Cancer Genomics.